The Merchant Lab

Principal Investigator

Sabeeha Merchant

Distinguished Professor of Biochemistry, Biophysics and Structural Biology
Distinguished Professor of Plant Biology
Faculty Senior Scientist, Lawrence Berkeley National Laboratory
Adjunct Professor of Biochemistry, UCLA
Warren C. Eveland Chair in Biological Sciences

BS and PhD, University of Wisconsin-Madison
Post-doctoral Scholar, Harvard University
Searle Scholar; National Institutes of Health Research Career Development Award; UCLA Faculty Career Development Awards; Guggenheim Foundation Fellow; Charles Albert Shull Award of ASPB; Herbert Newby McCoy Award; AAAS Fellow; ASPB Fellow; NAS Gilbert Morgan Smith Medal; ASPB Charles F. Kettering Award; Humboldt Forschungspreis (Alexander von Humboldt Foundation); Darbaker Prize from the Botanical Society of America; Elected to the U.S. National Academy of Sciences, Elected to the American Academy of Arts and Sciences; External Member, Max Planck Institute - Molecular Plant Physiology, Elected to Germany Academy of Sciences Leopoldina

sabeeha at berkeley dot edu

Post doctoral scholars + Research Scientists

Sean D. Gallaher
Research Scientist

BS and PhD, University of California, Los Angeles

I am interested in leveraging computational biology strategies (e.g. transcriptomics, genomics, etc.) to interrogate the inner workings of green algae.

 

gallaher at berkeley dot ed

Anne Glaesener
Project Scientist

B.Sc., M.Sc., Technical University Braunschweig, Germany (Biotechnology)
PhD, University of Kaiserslautern, Germany

I am the lab manager and admin coordinator of the Merchant Lab.

 

aglaesener at berkeley dot edu

Jeff Moseley
Research Scientist

B.Sc. University of California, San Diego, Biochemistry
Ph.D. University of California, Los Angeles, Molecular Biology
Post-doc Carnegie Institution for Science, Department of Plant Biology

Algae nutrition, photosynthesis, fatty acid and lipid biosynthesis, biotechnology applications

 

jlmoseley at berkeley dot edu

 

Usha Lingappa
Postdoctoral Scholar

BA in astrobiology from Hampshire College
PhD in geobiology from Caltech

For my postdoctoral research, I am using model algae to explore the disconnect between life in the natural environment and how we understand biology in the lab.

ufl at berkeley dot edu

 

Jon Lin
Post-doc - NIH Fellowship

Ph.D. in Biochemistry and Molecular Biology from Michigan State University

My research is dedicated to the development of oleaginous green algae as a sustainable platform for producing valuable lipid feedstock essential for both food and renewable energy. In addition to my work at the Sabeeha Merchant Lab, I am affiliated with the Trent Northen group at Lawrence Berkeley National Laboratory, where I conducts research on lipid metabolism.

 

linyt at berkeley dot edu

Graduate Students

Dimitrios Camacho
Graduate Student (Molecular and Cell Biology), Chancellor's Fellowship

B.S., Dominican University of California, Biological Sciences (Molecular Cell Biology)

I am interested in using multi-omics and synthetic biology approaches to interrogate various trace metal nutrient sensing and acquisition mechanisms of green algae. I am specifically interested in the transcriptomic responses of Chromochloris zofingiensis and Auxenochlorella protothecoides under Cu, Zn, and Fe deficiencies.

dimitrios_camacho at berkeley dot edu

Sunnyjoy Dupuis
Graduate Student (Microbiology)

B.S., California Polytechnic State University, San Luis Obispo (Microbiology, Minor of Environmental Studies)

I am interested in studying symbiosis between Chlamydomonas reinhardtii and rhizobial bacteria. How do these partners communicate to establish and maintain beneficial interactions? How does this change the metabolisms and genetic programs of each partner?  

sunnyjoy_dupuis at berkeley dot edu

Helen Liu
Graduate Student (Plant Biology, UC Berkeley)

B.S., University of Illinois at Urbana-Champaign (Crop Sciences, Plant Biotechnology and Molecular Biology)

My research focuses on understanding iron homeostasis in Chlamydomonas reinhardtii. I am interested in how photosynthesis, and generally the chloroplast, acclimates to iron deficiency by leveraging both Chlamydomonas and the halotolerant micro algae, Dunaliella.

hwliu2 at berkeley dot edu

Marco Dueñas
Graduate Student (Plant Biology)

B.S., University of California, Riverside (Biology) Summa Cum Laude

My research focuses on studying polycistronic expression in algae systems, both to uncover a mechanism and for synthetic biology application of rare products and designer lipids in the algae Auxenochlorella Protothecoides

marco.duenas at berkeley dot edu 

Lab Technician

Jude Edwards

Lab Technician 

University of California, Berkeley Molecular Environmental Biology B.S. with Honors

judith.edwards_23 at berkeley dot edu

Undergraduate Students

Jordan Chastain

Undergraduate Researcher

I am interested in understanding how Chlamydomonas interacts with heterotrophic bacteria in natural environments. I study microbial growth patterns and requirements for various nutrients, such as vitamins and carbon sources. I would also like to apply these findings to improving microalgae fitness in space life support systems.

jordanlynne at berkeley dot edu

 

Lauren Chiang

Undergraduate Researcher

laurentchiang at berkeley dot edu

 

Sonia Roedersheimer

Undergraduate Researcher

 

Alumni

Radhika Mehta
Postdoctoral Scholar

BSc (Chemistry) St. Stephen's College, University of Delhi
MSc by research (Inorganic Chemistry) University of Oxford
PhD (Chemistry) University of Texas at Austin

My research interests broadly include studying metals in biology- especially the interplay between the labile and metalloprotein-bound metal pools. In my postdoctoral research, I am studying the copper transcription factor, copper response regulator-1 (CRR1), responsible for controlling copper sensing and nutrition in Chlamydomonas reinhardtii. More specifically, I am employing molecular biology and genetics tools to delineate steps between copper sensing and CRR1 degradation.

radmehta at berkeley dot edu

 

Valle Ojeda Servian
Postdoctoral Scholar

B.S., M.S. and PhD, University of Seville, Spain

The objective of my project is to go beyond inventories of redox modified proteins by monitoring the proteome-wide dynamics of disulphide-dithiol status in the context of a diurnal metabolic cycle in the green alga Chlamydomonas reinhardtii. The findings will be important for modelling diurnal metabolic flux, which is useful for developing biotechnological strategies, whether synthetic biology or pharmacological, for manipulating metabolism for production of biofuels and bioproducts, where Chlamydomonas is a key reference organism.

valle.ojeser at berkeley dot edu

Stefan Schmollinger
Research Scientist

PhD, University of Kaiserslautern, Germany
Postdoctoral Scholar, UCLA

I am interested in acclimation responses to environmental cues in Chlamydomonas, and also elemental analysis in bulk or spatial distribution in eukaryotes. Currently searching for the point of intersection.

schmollinger at berkeley dot edu

Daniela Strenkert
Research Scientist

PhD, University of Kaiserslautern, Germany
Postdoctoral Scholar, UCLA

I am studying how transcriptional changes are orchestrated with changes of the epigenetic landscape in the eukaryotic, single-celled green algae Chlamydomonas. Chlamydomonas is a superior reference system since it offers all advantages of a single celled, eukaryotic, microbial culture system that can be combined with genome wide profiling approaches.

dstrenkert at berkeley dot edu

 

Openings

Positions for Ph.D. students and postdoctoral scholars may be available for all Merchant Lab projects.

Postdoctoral candidates with demonstrated research productivity (publication record) and expertise in biochemistry, cell biology, geochemistry, genetics, genomics, and microbiology are especially encouraged to apply. Please send the following to Sabeeha Merchant: a cover letter that describes your past research experience and motivation for applying to the Merchant Lab, a brief description of proposed research for your postdoctoral project, your most relevant published papers (for multi-author papers, please describe your contribution) as well as names and contact information for 3 or more potential references (letters are not needed during the initial stage).

Ph.D. candidates should apply to one of the following programs at UC Berkeley: Plant and Microbial Biology, Molecular and Cell Biology, Chemical Biology. All programs allow graduate students to rotate through multiple labs in the first year, providing a diversity of research experiences prior to selecting a lab.